· In DNA a phosphate group (PO 43) is attached to the 3′carbon of deoxyribose sugar and 5′carbon of another sugarTherefore, each strand contains 3′ end and 5′ end arranged in an alternate manner Strong negative charges of nucleic acid are due to the presence of phosphate groupsOf one phosphate group, one sugar ring, and one nitrogencontaining base • DNA has 4 types of bases Adenine, Thymine, Cytosine, and Guanine (A, T, C, and G) These bases have strict binding rules, as A only bonds with T (and vice versa), and C only bonds with G This is important for DNA replication to workAnswer to Label the DNA molecule Hydrogen bond Phosphate group Phosphodiester bond Deoxyribose sugar Nitrogenous base
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Model of dna and label the bases phosphate sugar groups hydrogen bonds and covalent bonds
Model of dna and label the bases phosphate sugar groups hydrogen bonds and covalent bonds-DNA Secondary structure is the set of interactions between bases, ie, which parts of strands are bound to each other In DNA double helix, the two strands of DNA are held together by hydrogen bondsThe nucleotides on one strand base pairs with the nucleotide on the other strand The secondary structure is responsible for the shape that the nucleic acid assumesHydrogen bond is a weak bond 4 The bond energy of covalent bond is between 100 to 1100 kJ/mol Bond energy of hydrogen bond is between 5 to 50 kJ/mol 5 Covalent bond is a primary bond Hydrogen bond is a secondary bond 6 Covalent bond changes the chemical properties of the bonding constituents



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Nucleotide 3 What is the special shape of DNA called ?DNA Model DNA MODELS DUE This week you will construct a 3D model of DNA out of household junk Make sure that you include the sugarphosphate backbone and the nitrogen bases These beautiful works of art and science will hang in the room indefinitely, so be proud of what you do and take the time necessary to construct a nice modelAnd to explain the significance of such interactions to the primary and secondary structures of DNA
Answer choices the model is inaccurate because the base pairs are incorrect the model is accurate because it contains correctly paired bases the model is accurate because it shows each base splitting to form a double helix the model is inaccurate because some typical bases in DNA are missing s Question 85 The two strands of DNA are held together with hydrogen bonds between the nitrogen basesBase Pair = A base pair is two chemical bases bonded to one another forming a "rung of the DNA ladder" The DNA molecule consists of two strands that wind around each other like a twisted ladder Each strand has a backbone made of alternating sugar (deoxyribose) and phosphate groups Attached to each sugar is one of four basesadenine (A
Deoxyribonucleic acid (DNA) stores information for the synthesis of specific proteins DNA has deoxyribose as its sugar DNA consists of a phosphate group, a sugar, and a nitrogenous base The structure of DNA is a helical, doublestranded macromolecule with bases projecting into the interior of the molecule3 On the ladder model of DNA label each of the bases with the letter A, T, C or G 4 Refer to Model 1 When one nucleotide contains adenine, what type of base is the adenine attached to on the opposite nucleotide strand?Base Pairing in DNA The nitrogen bases form the doublestrand of DNA through weak hydrogen bonds The nitrogen bases, however, have specific shapes and hydrogen bond properties so that guanine and cytosine only bond with each other, while adenine and thymine also bond exclusively This pairing off of the nitrogen bases is called complementarity




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1 Label EVERY sugar (S), phosphate (P), and nitrogen base (A, T, C, G) in the diagram below 2 Examine the objects inside the box labeled #2 What is this called?When nucleotides are incorporated into DNA, adjacent nucleotides are linked by a phosphodiester bond a covalent bond is formed between the 5' phosphate group of one nucleotide and the 3'OH group of another (see below) In this manner, each strand of DNA has a "backbone" of phosphatesugarphosphatesugarphosphate · The DNA double helix is stabilized primarily by two forces hydrogen bonds between nucleotides and basestacking interactions among aromatic nucleobases The four bases found in DNA are adenine (A), cytosine , guanine (G) and thymine (T)These four bases are attached to the sugarphosphate to form the complete nucleotide, as shown for adenosine monophosphate




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Label the entire DNA molecule (Be sure to include prime ends of a sugar molecule, pyrimidine and purine, nucleoside, nucleotide;1 Although weak, multiple hydrogen bonds are important in stabilizing the threedimensional shape of many biological molecules (Shape determines function "functional conformation") 2 Covalent bonds are usually very stable cells use protein catalysts called enzymes to "break" covalent bonds eg hydrolysi0519 · Watson and Crick model of DNA provides one of the best ways to demonstrate the structure of doublehelix DNAA DNA is a polymer composed by the combination of several monomer units (deoxyribonucleotides) linked by the phosphodiester bondIn the discovery of DNA, many scientists have contextualized the structure of DNA, its components and composition etc




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PRE uses blue light to break covalent bonds between thymine bases, allowing the hydrogen bonds to naturally reform Excision repair (dark reactivation) This repair process involves several enzymes a) An endonuclease called UvrABC 1 breaks the sugar phosphate backbone of the DNA strand near the dimer on each sideThe phosphate of one nucleotide is covalently bound (a bond in which one or more pairs of electrons are shared by two atoms) to the sugar of the next nucleotide The hydrogen bonds between phosphates cause the DNA strand to twist The nitrogenous bases point inward on the ladder and form pairs with bases on the other side, like rungsThe nucleotides that comprise DNA contain a nitrogenous base, a deoxyribose sugar, and a phosphate group which covalently link with other nucleotides to form phosphodiester bonds Nucleotide bases can be classified as purines (containing a doublering structure) or pyrimidines (containing a singlering structure)




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The rungs connecting the two sugarphosphate strands are created by pairs of nitrogenous bases These bases pair in very specific ways A always pairs with T and G with C Sugarphosphate Backbone Function The sugarphosphate backbone, as mentioned, is an important component of DNA's double helix structure · Adenine forms two hydrogen bonds with thymine and guanine forms three hydrogen bonds with cytosine The complementary base pairing in DNA is called WatsonCrick DNA base pairing model It brings two complementary DNA strands together, forming hydrogen bonds Hence, the final structure of DNA is doublestranded and antiparallelDNA has a doublehelix structure, with sugar and phosphate on the outside of the helix, forming the sugarphosphate backbone of the DNA The nitrogenous bases are stacked in the interior in pairs, like the steps of a staircase;




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